BDBM126715 US8785634, 21
SMILES: OC(=O)C(N1CCC2(CC1)OC(c1cccnc21)c1cc(Cl)cc(Cl)c1)c1ccc(OC(F)(F)F)cc1
InChI Key: InChIKey=LRAVDJRDDIEAQM-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal Pro-X carboxypeptidase (Homo sapiens (Human)) | BDBM126715 (US8785634, 21) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Corp US Patent | Assay Description The potency of compounds of formula I against PrCP was determined by a fluorescence intensity kinetic assay measuring the IC50 values of PrCP inhibit... | US Patent US8785634 (2014) BindingDB Entry DOI: 10.7270/Q2HH6HRS | |||||||||||
More data for this Ligand-Target Pair |