BDBM127306 US8791268, 7

SMILES: CC1CCN(CC1)c1nc(ccc1CNC(=O)Cc1cc(F)ccc1F)C(F)(F)F

InChI Key: InChIKey=STPIQBLJAJXJGI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127306   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM127306 (US8791268, 7) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Cc1cc(F)ccc1F)C(F)(F)F Show InChI InChI=1S/C21H22F5N3O/c1-13-6-8-29(9-7-13)20-14(2-5-18(28-20)21(24,25)26)12-27-19(30)11-15-10-16(22)3-4-17(15)23/h2-5,10,13H,6-9,11-12H2,1H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...				US Patent US8791268 (2014) BindingDB Entry DOI: 10.7270/Q2BV7F9D
					More data for this Ligand-Target Pair
Vanilloid receptor (Rattus norvegicus (rat))	BDBM127306 (US8791268, 7) Show SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Cc1cc(F)ccc1F)C(F)(F)F Show InChI InChI=1S/C21H22F5N3O/c1-13-6-8-29(9-7-13)20-14(2-5-18(28-20)21(24,25)26)12-27-19(30)11-15-10-16(22)3-4-17(15)23/h2-5,10,13H,6-9,11-12H2,1H3,(H,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of two substance additions. Initially, the compounds to be tested (10 uM) are pipeted onto the cells and the Ca2+ influx ...				US Patent US8791268 (2014) BindingDB Entry DOI: 10.7270/Q2BV7F9D
					More data for this Ligand-Target Pair