BDBM128225 2-(4-Chloro-3-fluoro-phenylamino)-7-hydroxy-4H-thiazolo[4,5-b]pyridin-5-one::2-(4-chloro-3-fluoro-anilino)-7-hydroxy-4H-thiazolo[4,5-b]pyridin-5-one::2-(4-chloro-3-fluoroanilino)-7-hydroxy-4H-[1,3]thiazolo[4,5-b]pyridin-5-one::2-(4-chloro-3-fluoroanilino)-7-hydroxy-4H-thiazolo[4,5-b]pyridin-5-one::2-[(4-chloranyl-3-fluoranyl-phenyl)amino]-7-oxidanyl-4H-[1,3]thiazolo[4,5-b]pyridin-5-one::MLS000332377::SMR000221708::cid_54677165

SMILES: Oc1cc(=O)[nH]c2nc(Nc3ccc(Cl)c(F)c3)sc12

InChI Key: InChIKey=HPWJLFZZVAHRFO-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 128225   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transthyretin (Homo sapiens (Human))	BDBM128225 (2-(4-Chloro-3-fluoro-phenylamino)-7-hydroxy-4H-thi...) Show SMILES Oc1cc(=O)[nH]c2nc(Nc3ccc(Cl)c(F)c3)sc12 Show InChI InChI=1S/C12H7ClFN3O2S/c13-6-2-1-5(3-7(6)14)15-12-17-11-10(20-12)8(18)4-9(19)16-11/h1-4H,(H3,15,16,17,18,19)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>1.67E+5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2DN43RH
					More data for this Ligand-Target Pair
Transthyretin (Homo sapiens (Human))	BDBM128225 (2-(4-Chloro-3-fluoro-phenylamino)-7-hydroxy-4H-thi...) Show SMILES Oc1cc(=O)[nH]c2nc(Nc3ccc(Cl)c(F)c3)sc12 Show InChI InChI=1S/C12H7ClFN3O2S/c13-6-2-1-5(3-7(6)14)15-12-17-11-10(20-12)8(18)4-9(19)16-11/h1-4H,(H3,15,16,17,18,19)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	>1.67E+5	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...				PubChem Bioassay (2014) BindingDB Entry DOI: 10.7270/Q2JD4VGV
					More data for this Ligand-Target Pair