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SMILES: CN(Cc1ccc(cc1)-c1nccnc1NS(=O)(=O)c1ccccc1C(F)(F)F)c1ccccc1

InChI Key: InChIKey=YPYKQYCRKFEEBJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128328   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM128328
PNG
(US8796280, 18)
Show SMILES CN(Cc1ccc(cc1)-c1nccnc1NS(=O)(=O)c1ccccc1C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C25H21F3N4O2S/c1-32(20-7-3-2-4-8-20)17-18-11-13-19(14-12-18)23-24(30-16-15-29-23)31-35(33,34)22-10-6-5-9-21(22)25(26,27)28/h2-16H,17H2,1H3,(H,30,31)
PDB

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Similars
US Patent
 400 -8.72n/an/an/an/an/a7.425



Merck Serono, S.A.

US Patent


Assay Description
The compounds of the present invention inhibit the binding of PGD2 to its receptor CRTH2. The inhibitory activity can be investigated by a radioligan...

US Patent US8796280 (2014)


BindingDB Entry DOI: 10.7270/Q2RV0MCF
More data for this
Ligand-Target Pair