BDBM128330 US8796280, 20

SMILES: Fc1ccc(OCc2ccc(cc2)-c2nccnc2NS(=O)(=O)c2ccccc2C(F)(F)F)cc1

InChI Key: InChIKey=HONHIFUUTQNHKE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM128330 (US8796280, 20) Show SMILES Fc1ccc(OCc2ccc(cc2)-c2nccnc2NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 Show InChI InChI=1S/C24H19F4N3O3S/c25-18-9-11-19(12-10-18)34-15-16-5-7-17(8-6-16)22-23(30-14-13-29-22)31-35(32,33)21-4-2-1-3-20(21)24(26,27)28/h1-14,35H,15H2,(H2,30,31,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	480	-8.61	n/a	n/a	n/a	n/a	n/a	7.4	25
Merck Serono, S.A. US Patent					Assay Description The compounds of the present invention inhibit the binding of PGD2 to its receptor CRTH2. The inhibitory activity can be investigated by a radioligan...				US Patent US8796280 (2014) BindingDB Entry DOI: 10.7270/Q2RV0MCF
					More data for this Ligand-Target Pair