BDBM128335 US8796280, 25

SMILES: FC(F)(F)c1ccccc1S(=O)(=O)Nc1nccnc1-c1ccc(Cn2c(cc3ccccc23)-c2ccccn2)cc1

InChI Key: InChIKey=KKWONWXJEYYZRS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM128335 (US8796280, 25) Show SMILES FC(F)(F)c1ccccc1S(=O)(=O)Nc1nccnc1-c1ccc(Cn2c(cc3ccccc23)-c2ccccn2)cc1 Show InChI InChI=1S/C31H24F3N5O2S/c32-31(33,34)24-8-2-4-11-28(24)42(40,41)38-30-29(36-17-18-37-30)22-14-12-21(13-15-22)20-39-26-10-3-1-7-23(26)19-27(39)25-9-5-6-16-35-25/h1-19,42H,20H2,(H2,37,38,40,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	850	-8.28	n/a	n/a	n/a	n/a	n/a	7.4	25
Merck Serono, S.A. US Patent					Assay Description The compounds of the present invention inhibit the binding of PGD2 to its receptor CRTH2. The inhibitory activity can be investigated by a radioligan...				US Patent US8796280 (2014) BindingDB Entry DOI: 10.7270/Q2RV0MCF
					More data for this Ligand-Target Pair