null
SMILES: COc1cc2ncc3n(C)nc(-c4ccc(cc4)C#N)c3c2cc1OCc1ccncc1
InChI Key: InChIKey=FPEGWNIIMWIHDK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human)) | BDBM128753 (US8802712, 11) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | <100 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Merck Patent GmbH US Patent | Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ... | US Patent US8802712 (2014) BindingDB Entry DOI: 10.7270/Q2VM49ZC | |||||||||||
More data for this Ligand-Target Pair |