BDBM128782 US8802712, 40

SMILES: COc1cc2ncc3n(C)nc(-c4ccc(cc4)C#N)c3c2cc1OCCN(C)C

InChI Key: InChIKey=CGLSRKYXSTWZTM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 128782   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM128782 (US8802712, 40) Show SMILES COc1cc2ncc3n(C)nc(-c4ccc(cc4)C#N)c3c2cc1OCCN(C)C Show InChI InChI=1S/C23H23N5O2/c1-27(2)9-10-30-21-11-17-18(12-20(21)29-4)25-14-19-22(17)23(26-28(19)3)16-7-5-15(13-24)6-8-16/h5-8,11-12,14H,9-10H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US8802712 (2014) BindingDB Entry DOI: 10.7270/Q2VM49ZC
					More data for this Ligand-Target Pair