null
SMILES: Fc1cc(ccc1Nc1ncc(cn1)C1CC1)[C@H]1CNCCO1
InChI Key: InChIKey=SPIXQSNBAKOSOQ-MRXNPFEDSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trace amine-associated receptor 1 (Mus musculus (Mouse)) | BDBM129477 (US8802673, 119) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.5 | -12.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc US Patent | Assay Description HEK-293 cells stably expressing rat TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ina... | US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trace amine-associated receptor 7b (Rattus norvegicus (Rat)) | BDBM129477 (US8802673, 119) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.10 | -11.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Hoffmann-La Roche Inc US Patent | Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37 C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat i... | US Patent US8802673 (2014) BindingDB Entry DOI: 10.7270/Q2348J2G | |||||||||||
More data for this Ligand-Target Pair |