BDBM129573 US8802663, 6
SMILES: Fc1ccc(cc1)-n1ncc(-c2nc(no2)-c2cc(F)ccc2F)c1-c1ccccc1
InChI Key: InChIKey=NSJKPBFOSRPEBW-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM129573![]() (US8802663, 6) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | 13 | -9.99 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Merck Serono SA US Patent | Assay Description Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 355-GTPgammaS binding studies. Cells wer... | US Patent US8802663 (2014) BindingDB Entry DOI: 10.7270/Q2ZC81K5 | |||||||||||
More data for this Ligand-Target Pair |