null
SMILES: COCc1c(cnn1C1CCCCC1)-c1nc(no1)-c1ccc(CCC(O)=O)cc1
InChI Key: InChIKey=BBVXGWDYDXVCOC-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sphingosine 1-phosphate receptor 1 (Homo sapiens (Human)) | BDBM129598 (US8802663, 139) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 393 | -8.12 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Merck Serono SA US Patent | Assay Description Receptor binding assay: Membranes were prepared from CHO cells expressing S1P1 or S1P3 for use in ligand and 355-GTPgammaS binding studies. Cells wer... | US Patent US8802663 (2014) BindingDB Entry DOI: 10.7270/Q2ZC81K5 | |||||||||||
More data for this Ligand-Target Pair |