BDBM130544 US8822447, 4::US9771375, Example 4
SMILES: CSc1nn(-c2ccccc2)c2cc(NC(=O)NC3CCNC3)ccc12
InChI Key: InChIKey=ZDOSUEBKHPEOCW-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ketohexokinase (KHK) Isoform C (Homo sapiens (Human)) | BDBM130544![]() (US8822447, 4 | US9771375, Example 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Janssen Pharmaceutica NV US Patent | Assay Description An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... | US Patent US9771375 (2017) BindingDB Entry DOI: 10.7270/Q20R9RJW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Ketohexokinase (KHK) Isoform C (Homo sapiens (Human)) | BDBM130544![]() (US8822447, 4 | US9771375, Example 4) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | 25 |
Janssen Pharmaceutica NV US Patent | Assay Description An enzymatic assay was developed to measure KHK-mediated conversion of D-fructose to Fructose-1-P (F-1-P) using High Throughput Mass Spectroscopy (HT... | US Patent US8822447 (2014) BindingDB Entry DOI: 10.7270/Q2M0443Q | |||||||||||
More data for this Ligand-Target Pair |