BDBM135774 US10179804, Example 159::US10632171, Peptide No. 159::US8846601, 159::US9458201, 159

SMILES: CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O

InChI Key:

Data: 8 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 135774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palatin Technologies, Inc. US Patent					Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...				US Patent US10632171 (2020)
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-11.9	n/a	n/a	n/a	n/a	n/a	7.5	37
Palatin Technologies, Inc. US Patent					Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...				US Patent US9458201 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N79
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Palatin Technologies, Inc. US Patent					Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...				US Patent US8846601 (2014) BindingDB Entry DOI: 10.7270/Q2SF2TWK
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palatin Technologies, Inc. US Patent					Assay Description Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...				US Patent US10179804 (2019) BindingDB Entry DOI: 10.7270/Q24T6MFP
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palatin Technologies, Inc. US Patent					Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...				US Patent US10632171 (2020)
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	133	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
Palatin Technologies, Inc. US Patent					Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...				US Patent US8846601 (2014) BindingDB Entry DOI: 10.7270/Q2SF2TWK
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	133	-9.75	n/a	n/a	n/a	n/a	n/a	7.5	37
Palatin Technologies, Inc. US Patent					Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...				US Patent US9458201 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N79
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Palatin Technologies, Inc. US Patent					Assay Description A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...				US Patent US10632171 (2020)
					More data for this Ligand-Target Pair
Melanocyte-stimulating hormone receptor (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	26	n/a	n/a	7.5	37
Palatin Technologies, Inc. US Patent					Assay Description Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...				US Patent US9458201 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N79
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM135774 (US10179804, Example 159 | US10632171, Peptide No. ...) Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCNC(=O)CCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCC(N)=O)NC1=O)C(N)=O |r| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	n/a	0.825	n/a	n/a	7.5	37
Palatin Technologies, Inc. US Patent					Assay Description Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...				US Patent US9458201 (2016) BindingDB Entry DOI: 10.7270/Q2HT2N79
					More data for this Ligand-Target Pair