BDBM136359 US8859534, 45

SMILES: COc1cccc(CCN2CCN(CC2)c2cccc3cc(oc23)C(=O)N2CCC2)n1

InChI Key: InChIKey=CIWOESWFVHEUMU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 136359   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (5HT1A) (Cricetulus griseus (Chinese hamster) (Cricetulus b...)	BDBM136359 (US8859534, 45) Show SMILES COc1cccc(CCN2CCN(CC2)c2cccc3cc(oc23)C(=O)N2CCC2)n1 Show InChI InChI=1S/C24H28N4O3/c1-30-22-8-3-6-19(25-22)9-12-26-13-15-27(16-14-26)20-7-2-5-18-17-21(31-23(18)20)24(29)28-10-4-11-28/h2-3,5-8,17H,4,9-16H2,1H3	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.340	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Acturum Life Science AB US Patent					Assay Description Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...				US Patent US8859534 (2014) BindingDB Entry DOI: 10.7270/Q23R0RKV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (5HT1B) (Cricetulus griseus (Chinese hamster) (Cricetulus b...)	BDBM136359 (US8859534, 45) Show SMILES COc1cccc(CCN2CCN(CC2)c2cccc3cc(oc23)C(=O)N2CCC2)n1 Show InChI InChI=1S/C24H28N4O3/c1-30-22-8-3-6-19(25-22)9-12-26-13-15-27(16-14-26)20-7-2-5-18-17-21(31-23(18)20)24(29)28-10-4-11-28/h2-3,5-8,17H,4,9-16H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.40	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Acturum Life Science AB US Patent					Assay Description Assays that were used to measure affinity of the compounds of the present invention for 5-HT1A and 5-HT1B receptors are described in J. Recept Signal...				US Patent US8859534 (2014) BindingDB Entry DOI: 10.7270/Q23R0RKV
					More data for this Ligand-Target Pair