BDBM13706 1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxyphenyl}carbonyl)-4-(pyridin-4-ylmethyl)piperazine::3-Oxybenzamide 92

SMILES: COc1cc(cc(OCCc2ccc(Cl)cc2Cl)c1OC)C(=O)N1CCN(Cc2ccncc2)CC1

InChI Key: InChIKey=FISLUEWNTGQBAP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13706   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13706 (1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxy...) Show SMILES COc1cc(cc(OCCc2ccc(Cl)cc2Cl)c1OC)C(=O)N1CCN(Cc2ccncc2)CC1 Show InChI InChI=1S/C27H29Cl2N3O4/c1-34-24-15-21(27(33)32-12-10-31(11-13-32)18-19-5-8-30-9-6-19)16-25(26(24)35-2)36-14-7-20-3-4-22(28)17-23(20)29/h3-6,8-9,15-17H,7,10-14,18H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	167	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 48: 3290-312 (2005) Article DOI: 10.1021/jm049187l BindingDB Entry DOI: 10.7270/Q28C9THZ
					More data for this Ligand-Target Pair