null

SMILES: CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CCC(N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(CCc2ccc(NC(=O)N3CC[C@H]4CC[C@H](N4C(=O)[C@H](C3)NC(=O)[C@H](C)NC)C(=O)NC(c3ccccc3)c3ccccc3)cc2)cc1

InChI Key: InChIKey=XZDUYCPLOANNJY-QCDGKUOLSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139072   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase XIAP (Homo sapiens (Human))	BDBM139072 (US8883771, 18) Show SMILES CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CCC(N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(CCc2ccc(NC(=O)N3CC[C@H]4CC[C@H](N4C(=O)[C@H](C3)NC(=O)[C@H](C)NC)C(=O)NC(c3ccccc3)c3ccccc3)cc2)cc1 |r| Show InChI InChI=1S/C70H82N12O8/c1-45(71-3)63(83)75-57-43-79(41-39-55-35-37-59(81(55)67(57)87)65(85)77-61(49-17-9-5-10-18-49)50-19-11-6-12-20-50)69(89)73-53-31-27-47(28-32-53)25-26-48-29-33-54(34-30-48)74-70(90)80-42-40-56-36-38-60(82(56)68(88)58(44-80)76-64(84)46(2)72-4)66(86)78-62(51-21-13-7-14-22-51)52-23-15-8-16-24-52/h5-24,27-34,45-46,55-62,71-72H,25-26,35-44H2,1-4H3,(H,73,89)(H,74,90)(H,75,83)(H,76,84)(H,77,85)(H,78,86)/t45-,46-,55+,56+,57-,58-,59-,60?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	7.5	n/a
The Regents of the University of Michigan US Patent					Assay Description Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...				US Patent US8883771 (2014) BindingDB Entry DOI: 10.7270/Q2C24V4C
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 3 (Homo sapiens (Human))	BDBM139072 (US8883771, 18) Show SMILES CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CCC(N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(CCc2ccc(NC(=O)N3CC[C@H]4CC[C@H](N4C(=O)[C@H](C3)NC(=O)[C@H](C)NC)C(=O)NC(c3ccccc3)c3ccccc3)cc2)cc1 |r| Show InChI InChI=1S/C70H82N12O8/c1-45(71-3)63(83)75-57-43-79(41-39-55-35-37-59(81(55)67(57)87)65(85)77-61(49-17-9-5-10-18-49)50-19-11-6-12-20-50)69(89)73-53-31-27-47(28-32-53)25-26-48-29-33-54(34-30-48)74-70(90)80-42-40-56-36-38-60(82(56)68(88)58(44-80)76-64(84)46(2)72-4)66(86)78-62(51-21-13-7-14-22-51)52-23-15-8-16-24-52/h5-24,27-34,45-46,55-62,71-72H,25-26,35-44H2,1-4H3,(H,73,89)(H,74,90)(H,75,83)(H,76,84)(H,77,85)(H,78,86)/t45-,46-,55+,56+,57-,58-,59-,60?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	7.5	n/a
The Regents of the University of Michigan US Patent					Assay Description Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...				US Patent US8883771 (2014) BindingDB Entry DOI: 10.7270/Q2C24V4C
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 2 (Homo sapiens (Human))	BDBM139072 (US8883771, 18) Show SMILES CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CCC(N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)Nc1ccc(CCc2ccc(NC(=O)N3CC[C@H]4CC[C@H](N4C(=O)[C@H](C3)NC(=O)[C@H](C)NC)C(=O)NC(c3ccccc3)c3ccccc3)cc2)cc1 |r| Show InChI InChI=1S/C70H82N12O8/c1-45(71-3)63(83)75-57-43-79(41-39-55-35-37-59(81(55)67(57)87)65(85)77-61(49-17-9-5-10-18-49)50-19-11-6-12-20-50)69(89)73-53-31-27-47(28-32-53)25-26-48-29-33-54(34-30-48)74-70(90)80-42-40-56-36-38-60(82(56)68(88)58(44-80)76-64(84)46(2)72-4)66(86)78-62(51-21-13-7-14-22-51)52-23-15-8-16-24-52/h5-24,27-34,45-46,55-62,71-72H,25-26,35-44H2,1-4H3,(H,73,89)(H,74,90)(H,75,83)(H,76,84)(H,77,85)(H,78,86)/t45-,46-,55+,56+,57-,58-,59-,60?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<300	n/a	n/a	n/a	n/a	7.5	n/a
The Regents of the University of Michigan US Patent					Assay Description Binding affinities of the present compounds to XIAP linker-BIR2-BIR3 (residues 120-356), cIAP1-BIR3 (residues 253-363), and cIAP-2 BIR3 (residues 238...				US Patent US8883771 (2014) BindingDB Entry DOI: 10.7270/Q2C24V4C
					More data for this Ligand-Target Pair