BDBM139409 US8889671, 39

SMILES: C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2[C@H](COC2=O)C=C)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=KSRZROMUZUXSSR-YFEKEUHLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139409   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase Subunit A (Escherichia coli (strain K12))	BDBM139409 (US8889671, 39) Show SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2[C@H](COC2=O)C=C)C(=O)NC(=O)NC1=O |r| Show InChI InChI=1S/C23H22FN5O7/c1-4-12-8-34-22(33)29(12)18-13-5-11-6-23(19(30)25-21(32)26-20(23)31)17-10(3)35-9(2)7-28(17)15(11)14(24)16(13)36-27-18/h4-5,9-10,12,17H,1,6-8H2,2-3H3,(H2,25,26,30,31,32)/t9-,10+,12+,17-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	97	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...				US Patent US8889671 (2014) BindingDB Entry DOI: 10.7270/Q22J69JX
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