BDBM139418 US8889671, 49

SMILES: CCOC[C@H]1COC(=O)N1c1noc2c(F)c3N4C[C@@H](C)O[C@@H](C)[C@@H]4C4(Cc3cc12)C(=O)NC(=O)NC4=O

InChI Key: InChIKey=QJLWNAJTGLKUPD-KACXOKKCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139418   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase Subunit A (Escherichia coli (strain K12))	BDBM139418 (US8889671, 49) Show SMILES CCOC[C@H]1COC(=O)N1c1noc2c(F)c3N4C[C@@H](C)O[C@@H](C)[C@@H]4C4(Cc3cc12)C(=O)NC(=O)NC4=O |r| Show InChI InChI=1S/C24H26FN5O8/c1-4-35-8-13-9-36-23(34)30(13)19-14-5-12-6-24(20(31)26-22(33)27-21(24)32)18-11(3)37-10(2)7-29(18)16(12)15(25)17(14)38-28-19/h5,10-11,13,18H,4,6-9H2,1-3H3,(H2,26,27,31,32,33)/t10-,11+,13+,18-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...				US Patent US8889671 (2014) BindingDB Entry DOI: 10.7270/Q22J69JX
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