BDBM139447 US8889671, 61::US8889671, 63

SMILES: C[C@@H]1CN2C([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2[C@@H](COC2=O)c2ncccn2)C(=O)NC(=O)NC1=O

InChI Key: InChIKey=XNHIBFIYRMMRCU-KISLSHQNSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 139447   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA Gyrase Subunit A (Escherichia coli (strain K12))	BDBM139447 (US8889671, 61 | US8889671, 63) Show SMILES C[C@@H]1CN2C([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2[C@@H](COC2=O)c2ncccn2)C(=O)NC(=O)NC1=O |r| Show InChI InChI=1S/C25H22FN7O7/c1-10-8-32-16-12(7-25(18(32)11(2)39-10)21(34)29-23(36)30-22(25)35)6-13-17(15(16)26)40-31-20(13)33-14(9-38-24(33)37)19-27-4-3-5-28-19/h3-6,10-11,14,18H,7-9H2,1-2H3,(H2,29,30,34,35,36)/t10-,11+,14+,18?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...				US Patent US8889671 (2014) BindingDB Entry DOI: 10.7270/Q22J69JX
					More data for this Ligand-Target Pair
DNA Gyrase Subunit A (Escherichia coli (strain K12))	BDBM139447 (US8889671, 61 | US8889671, 63) Show SMILES C[C@@H]1CN2C([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2[C@@H](COC2=O)c2ncccn2)C(=O)NC(=O)NC1=O |r| Show InChI InChI=1S/C25H22FN7O7/c1-10-8-32-16-12(7-25(18(32)11(2)39-10)21(34)29-23(36)30-22(25)35)6-13-17(15(16)26)40-31-20(13)33-14(9-38-24(33)37)19-27-4-3-5-28-19/h3-6,10-11,14,18H,7-9H2,1-2H3,(H2,29,30,34,35,36)/t10-,11+,14+,18?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...				US Patent US8889671 (2014) BindingDB Entry DOI: 10.7270/Q22J69JX
					More data for this Ligand-Target Pair