BDBM139908 US8895745, 59
SMILES: Fc1ccc(cc1)-c1ccn2c(cnc2c1)-c1cccc(NC(=O)NCC(F)(F)F)c1
InChI Key: InChIKey=BCAIAJFLSCRMPZ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fibroblast growth factor receptor 3 (Homo sapiens (Human)) | BDBM139908![]() (US8895745, 59) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Astex Therapeutics Limited US Patent | Assay Description Enzymes (from Upstate) were prepared at 2x final concentration in 1x kinase assay buffer (as described below). Enzymes were then incubated with test ... | US Patent US8895745 (2014) BindingDB Entry DOI: 10.7270/Q2833QQC | |||||||||||
More data for this Ligand-Target Pair |