BDBM141060 US8653100, 14

SMILES: Fc1cc2CCNC(c2cc1OCCNS(=O)(=O)c1cccnc1)C1(CCC1)c1ccc(Cl)cc1

InChI Key: InChIKey=FSMLMGRCZLNPAQ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM141060 (US8653100, 14) Show SMILES Fc1cc2CCNC(c2cc1OCCNS(=O)(=O)c1cccnc1)C1(CCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H27ClFN3O3S/c27-20-6-4-19(5-7-20)26(9-2-10-26)25-22-16-24(23(28)15-18(22)8-12-30-25)34-14-13-31-35(32,33)21-3-1-11-29-17-21/h1,3-7,11,15-17,25,30-31H,2,8-10,12-14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
					More data for this Ligand-Target Pair
Glycine transporter 1 (Homo sapiens (Human))	BDBM141060 (US8653100, 14) Show SMILES Fc1cc2CCNC(c2cc1OCCNS(=O)(=O)c1cccnc1)C1(CCC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C26H27ClFN3O3S/c27-20-6-4-19(5-7-20)26(9-2-10-26)25-22-16-24(23(28)15-18(22)8-12-30-25)34-14-13-31-35(32,33)21-3-1-11-29-17-21/h1,3-7,11,15-17,25,30-31H,2,8-10,12-14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description [3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 ...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
					More data for this Ligand-Target Pair