BDBM141181 US8653100, 92

SMILES: Clc1ccc(cc1)C1(CCC1)C1NCCc2ccc(cc12)C#N

InChI Key: InChIKey=XHHNHZKCNHTKRE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM141181 (US8653100, 92) Show SMILES Clc1ccc(cc1)C1(CCC1)C1NCCc2ccc(cc12)C#N Show InChI InChI=1S/C20H19ClN2/c21-17-6-4-16(5-7-17)20(9-1-10-20)19-18-12-14(13-22)2-3-15(18)8-11-23-19/h2-7,12,19,23H,1,8-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
					More data for this Ligand-Target Pair