BDBM141251 US8653100, 145

SMILES: CCCS(=O)(=O)NCCOc1ccc2CCNC(C(C)c3ccc(Cl)cc3)c2c1

InChI Key: InChIKey=CDJZSSOSGZCBKM-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycine transporter 1 (Homo sapiens (Human))	BDBM141251 (US8653100, 145) Show SMILES CCCS(=O)(=O)NCCOc1ccc2CCNC(C(C)c3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C22H29ClN2O3S/c1-3-14-29(26,27)25-12-13-28-20-9-6-18-10-11-24-22(21(18)15-20)16(2)17-4-7-19(23)8-5-17/h4-9,15-16,22,24-25H,3,10-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
					More data for this Ligand-Target Pair
Glycine transporter 1 (Homo sapiens (Human))	BDBM141251 (US8653100, 145) Show SMILES CCCS(=O)(=O)NCCOc1ccc2CCNC(C(C)c3ccc(Cl)cc3)c2c1 Show InChI InChI=1S/C22H29ClN2O3S/c1-3-14-29(26,27)25-12-13-28-20-9-6-18-10-11-24-22(21(18)15-20)16(2)17-4-7-19(23)8-5-17/h4-9,15-16,22,24-25H,3,10-14H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description [3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 ...				US Patent US8653100 (2014) BindingDB Entry DOI: 10.7270/Q2JD4VH9
					More data for this Ligand-Target Pair