BDBM141512 US8921373, 1::US8921373, 9

SMILES: FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)cc1Cl

InChI Key: InChIKey=DCDIFSMOVXBCHH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM141512 (US8921373, 1 | US8921373, 9) Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)cc1Cl |c:14| Show InChI InChI=1S/C18H14Cl2F3N3O/c19-14-2-1-7-24-16(14)11-5-8-26(9-6-11)17(27)25-12-3-4-13(15(20)10-12)18(21,22)23/h1-5,7,10H,6,8-9H2,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	77	n/a	n/a	n/a	n/a	7.4	n/a
Shionogi & Co., Ltd. US Patent					Assay Description Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...				US Patent US8921373 (2014) BindingDB Entry DOI: 10.7270/Q28051BW
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM141512 (US8921373, 1 | US8921373, 9) Show SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)cc1Cl |c:14| Show InChI InChI=1S/C18H14Cl2F3N3O/c19-14-2-1-7-24-16(14)11-5-8-26(9-6-11)17(27)25-12-3-4-13(15(20)10-12)18(21,22)23/h1-5,7,10H,6,8-9H2,(H,25,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	139	n/a	n/a	n/a	n/a	7.4	n/a
Shionogi & Co., Ltd. US Patent					Assay Description Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...				US Patent US8921373 (2014) BindingDB Entry DOI: 10.7270/Q28051BW
					More data for this Ligand-Target Pair