BDBM141513 US8921373, ABL
SMILES: OC[C@H](O)C(F)(F)c1cnc(C2=CCN(CC2)C(=O)Nc2ccc(OC(F)(F)F)cn2)c(Cl)c1
InChI Key: InChIKey=PIKDFWUHMDVHCR-HNNXBMFYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM141513![]() (US8921373, ABL) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 46 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Shionogi & Co., Ltd. US Patent | Assay Description Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect... | US Patent US8921373 (2014) BindingDB Entry DOI: 10.7270/Q28051BW | |||||||||||
More data for this Ligand-Target Pair |