BDBM141515 US8921373, ACU

SMILES: COC1CN(CCN1C(=O)Nc1nc2ccc(F)cc2s1)c1ncc(C[C@@H](O)CO)cc1Cl

InChI Key: InChIKey=UCVYUQYQRCZBGK-IKJXHCRLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM141515 (US8921373, ACU) Show SMILES COC1CN(CCN1C(=O)Nc1nc2ccc(F)cc2s1)c1ncc(C[C@@H](O)CO)cc1Cl |r| Show InChI InChI=1S/C21H23ClFN5O4S/c1-32-18-10-27(19-15(22)7-12(9-24-19)6-14(30)11-29)4-5-28(18)21(31)26-20-25-16-3-2-13(23)8-17(16)33-20/h2-3,7-9,14,18,29-30H,4-6,10-11H2,1H3,(H,25,26,31)/t14-,18?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.4	n/a
Shionogi & Co., Ltd. US Patent					Assay Description Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...				US Patent US8921373 (2014) BindingDB Entry DOI: 10.7270/Q28051BW
					More data for this Ligand-Target Pair