BDBM141516 US8921373, 3

SMILES: C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(F)cc2s1)c1ncccc1Cl

InChI Key: InChIKey=GNOUYVAOSUDCCM-LLVKDONJSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM141516 (US8921373, 3) Show SMILES C[C@@H]1CN(CCN1C(=O)Nc1nc2ccc(F)cc2s1)c1ncccc1Cl |r| Show InChI InChI=1S/C18H17ClFN5OS/c1-11-10-24(16-13(19)3-2-6-21-16)7-8-25(11)18(26)23-17-22-14-5-4-12(20)9-15(14)27-17/h2-6,9,11H,7-8,10H2,1H3,(H,22,23,26)/t11-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	7.4	n/a
Shionogi & Co., Ltd. US Patent					Assay Description Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...				US Patent US8921373 (2014) BindingDB Entry DOI: 10.7270/Q28051BW
					More data for this Ligand-Target Pair