BDBM141521 US8921373, AEF
SMILES: OC[C@@H](O)Cc1cnc(c(Cl)c1)C1(F)CCN(CC1)C(=O)Nc1nc2ccc(cc2s1)C(F)(F)F
InChI Key: InChIKey=HOBNHZJMZWOWHN-AWEZNQCLSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human)) | BDBM141521 (US8921373, AEF) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 614 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Shionogi & Co., Ltd. US Patent | Assay Description Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect... | US Patent US8921373 (2014) BindingDB Entry DOI: 10.7270/Q28051BW | |||||||||||
More data for this Ligand-Target Pair |