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SMILES: OCC(O)Cc1cnc(C2CCN(CC2)C(=O)Nc2nc3cc(F)ccc3s2)c(Cl)c1

InChI Key: InChIKey=DTLXVRAZXBRXNZ-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141532   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM141532
PNG
(US8921373, AAD)
Show SMILES OCC(O)Cc1cnc(C2CCN(CC2)C(=O)Nc2nc3cc(F)ccc3s2)c(Cl)c1
Show InChI InChI=1S/C21H22ClFN4O3S/c22-16-8-12(7-15(29)11-28)10-24-19(16)13-3-5-27(6-4-13)21(30)26-20-25-17-9-14(23)1-2-18(17)31-20/h1-2,8-10,13,15,28-29H,3-7,11H2,(H,25,26,30)
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Similars
US Patent
n/an/a 5n/an/an/an/a7.4n/a



Shionogi & Co., Ltd.

US Patent


Assay Description
Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...

US Patent US8921373 (2014)


BindingDB Entry DOI: 10.7270/Q28051BW
More data for this
Ligand-Target Pair