BDBM141553 US8921389, 9::US9695170 9

SMILES: OC(=O)CNC(=O)c1nc(C#N)c2N(Cc3ccccc3)C(=O)CCc2c1O

InChI Key: InChIKey=BVQDKTPHRASCEM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141553   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141553 (US8921389, 9 | US9695170 9) Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2N(Cc3ccccc3)C(=O)CCc2c1O Show InChI InChI=1S/C19H16N4O5/c20-8-13-17-12(18(27)16(22-13)19(28)21-9-15(25)26)6-7-14(24)23(17)10-11-4-2-1-3-5-11/h1-5,27H,6-7,9-10H2,(H,21,28)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9695170 (2017) BindingDB Entry DOI: 10.7270/Q2P55KN0
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141553 (US8921389, 9 | US9695170 9) Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2N(Cc3ccccc3)C(=O)CCc2c1O Show InChI InChI=1S/C19H16N4O5/c20-8-13-17-12(18(27)16(22-13)19(28)21-9-15(25)26)6-7-14(24)23(17)10-11-4-2-1-3-5-11/h1-5,27H,6-7,9-10H2,(H,21,28)(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	7.4	n/a
Fibrogen, Inc. US Patent					Assay Description Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...				US Patent US8921389 (2014) BindingDB Entry DOI: 10.7270/Q20G3HV0
					More data for this Ligand-Target Pair