BDBM141558 US8921389, 14::US9695170 42

SMILES: OC(=O)CNC(=O)c1nc(C#N)c2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1

InChI Key: InChIKey=KJGUAAQVEYKPAA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 141558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141558 (US8921389, 14 | US9695170 42) Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1 Show InChI InChI=1S/C25H18N4O5/c26-12-19-22-18(23(32)21(28-19)24(33)27-13-20(30)31)11-17(16-9-5-2-6-10-16)25(34)29(22)14-15-7-3-1-4-8-15/h1-11,32H,13-14H2,(H,27,33)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	n/a
Fibrogen, Inc. US Patent					Assay Description Ketoglutaric acid alpha -[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources,...				US Patent US8921389 (2014) BindingDB Entry DOI: 10.7270/Q20G3HV0
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141558 (US8921389, 14 | US9695170 42) Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1 Show InChI InChI=1S/C25H18N4O5/c26-12-19-22-18(23(32)21(28-19)24(33)27-13-20(30)31)11-17(16-9-5-2-6-10-16)25(34)29(22)14-15-7-3-1-4-8-15/h1-11,32H,13-14H2,(H,27,33)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.29E+5	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9695170 (2017) BindingDB Entry DOI: 10.7270/Q2P55KN0
					More data for this Ligand-Target Pair
Egl nine homolog 1 (Homo sapiens (Human))	BDBM141558 (US8921389, 14 | US9695170 42) Show SMILES OC(=O)CNC(=O)c1nc(C#N)c2n(Cc3ccccc3)c(=O)c(cc2c1O)-c1ccccc1 Show InChI InChI=1S/C25H18N4O5/c26-12-19-22-18(23(32)21(28-19)24(33)27-13-20(30)31)11-17(16-9-5-2-6-10-16)25(34)29(22)14-15-7-3-1-4-8-15/h1-11,32H,13-14H2,(H,27,33)(H,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.4	n/a
FibroGen, Inc. US Patent					Assay Description Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...				US Patent US9695170 (2017) BindingDB Entry DOI: 10.7270/Q2P55KN0
					More data for this Ligand-Target Pair