null

SMILES: NC(=O)C(N[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1cc(F)cc(F)c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 141914   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM141914 (US8921559, 1a | US8921559, 1b | US8921559, 2b) Show SMILES NC(=O)C(N[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1cc(F)cc(F)c1 |r,wU:5.4,wD:8.11,(-.82,1.19,;-2.15,.42,;-3.48,1.19,;-2.15,-1.12,;-3.48,-1.89,;-4.82,-1.12,;-6.15,-1.89,;-7.48,-1.12,;-7.48,.42,;-6.15,1.19,;-4.82,.42,;-8.82,1.19,;-10.28,.71,;-11.19,1.96,;-10.28,3.2,;-10.6,4.71,;-9.46,5.74,;-7.99,5.27,;-7.67,3.76,;-8.82,2.73,;-.82,-1.89,;-.82,-3.43,;.52,-4.2,;1.85,-3.43,;1.85,-1.89,;.52,-1.12,;3.19,-4.2,;3.19,-5.74,;4.52,-3.43,;5.85,-4.2,;7.19,-3.43,;8.52,-4.2,;9.85,-3.43,;11.19,-4.2,;9.85,-1.89,;8.52,-1.12,;8.52,.42,;7.19,-1.89,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica NV US Patent					Assay Description MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...				US Patent US8921559 (2014) BindingDB Entry DOI: 10.7270/Q270804M
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM141914 (US8921559, 1a | US8921559, 1b | US8921559, 2b) Show SMILES NC(=O)C(N[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1cc(F)cc(F)c1 |r,wU:5.4,wD:8.11,(-.82,1.19,;-2.15,.42,;-3.48,1.19,;-2.15,-1.12,;-3.48,-1.89,;-4.82,-1.12,;-6.15,-1.89,;-7.48,-1.12,;-7.48,.42,;-6.15,1.19,;-4.82,.42,;-8.82,1.19,;-10.28,.71,;-11.19,1.96,;-10.28,3.2,;-10.6,4.71,;-9.46,5.74,;-7.99,5.27,;-7.67,3.76,;-8.82,2.73,;-.82,-1.89,;-.82,-3.43,;.52,-4.2,;1.85,-3.43,;1.85,-1.89,;.52,-1.12,;3.19,-4.2,;3.19,-5.74,;4.52,-3.43,;5.85,-4.2,;7.19,-3.43,;8.52,-4.2,;9.85,-3.43,;11.19,-4.2,;9.85,-1.89,;8.52,-1.12,;8.52,.42,;7.19,-1.89,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	187	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica NV US Patent					Assay Description MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...				US Patent US8921559 (2014) BindingDB Entry DOI: 10.7270/Q270804M
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM141914 (US8921559, 1a | US8921559, 1b | US8921559, 2b) Show SMILES NC(=O)C(N[C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)\C=C\c1cc(F)cc(F)c1 |r,wU:5.4,wD:8.11,(-.82,1.19,;-2.15,.42,;-3.48,1.19,;-2.15,-1.12,;-3.48,-1.89,;-4.82,-1.12,;-6.15,-1.89,;-7.48,-1.12,;-7.48,.42,;-6.15,1.19,;-4.82,.42,;-8.82,1.19,;-10.28,.71,;-11.19,1.96,;-10.28,3.2,;-10.6,4.71,;-9.46,5.74,;-7.99,5.27,;-7.67,3.76,;-8.82,2.73,;-.82,-1.89,;-.82,-3.43,;.52,-4.2,;1.85,-3.43,;1.85,-1.89,;.52,-1.12,;3.19,-4.2,;3.19,-5.74,;4.52,-3.43,;5.85,-4.2,;7.19,-3.43,;8.52,-4.2,;9.85,-3.43,;11.19,-4.2,;9.85,-1.89,;8.52,-1.12,;8.52,.42,;7.19,-1.89,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica NV US Patent					Assay Description MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...				US Patent US8921559 (2014) BindingDB Entry DOI: 10.7270/Q270804M
					More data for this Ligand-Target Pair