null

SMILES: NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)Nc1cccc(c1)C(F)(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141924   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM141924 (US8921559, 16) Show SMILES NC(=O)C(NC1CCC(CC1)c1c[nH]c2ccccc12)C1CCN(CC1)C(=O)Nc1cccc(c1)C(F)(F)F |(-.82,1.57,;-2.15,.8,;-3.48,1.57,;-2.15,-.74,;-3.48,-1.51,;-4.82,-.74,;-6.15,-1.51,;-7.48,-.74,;-7.48,.8,;-6.15,1.57,;-4.82,.8,;-8.82,1.57,;-10.28,1.1,;-11.19,2.34,;-10.28,3.59,;-10.6,5.1,;-9.46,6.13,;-7.99,5.65,;-7.67,4.14,;-8.82,3.11,;-.82,-1.51,;-.82,-3.05,;.52,-3.82,;1.85,-3.05,;1.85,-1.51,;.52,-.74,;3.19,-3.82,;3.19,-5.36,;4.52,-3.05,;5.85,-3.82,;5.85,-5.36,;7.19,-6.13,;8.52,-5.36,;8.52,-3.82,;7.19,-3.05,;9.85,-3.05,;11.19,-3.82,;9.85,-1.51,;11.19,-2.28,)| Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	37
Janssen Pharmaceutica NV US Patent					Assay Description MCP-1 Receptor Binding Assay in THP-1 Cells Human monocytic cell line THP-1 cells were obtained from American Type Culture Collection (Manassas, Va.,...				US Patent US8921559 (2014) BindingDB Entry DOI: 10.7270/Q270804M
					More data for this Ligand-Target Pair