BDBM141995 US8927536, 1

SMILES: CC1(CO)Cc2nnc(n2CCS1)C1(CC1)c1ccc(cc1)-c1ccccc1

InChI Key: InChIKey=KJIBRMRRCCDONN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141995   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM141995 (US8927536, 1) Show SMILES CC1(CO)Cc2nnc(n2CCS1)C1(CC1)c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C23H25N3OS/c1-22(16-27)15-20-24-25-21(26(20)13-14-28-22)23(11-12-23)19-9-7-18(8-10-19)17-5-3-2-4-6-17/h2-10,27H,11-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	7.4	25
Daiichi Sankyo Company, Limited US Patent					Assay Description A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 µL, and all the samples were diluted with an assay buffe...				US Patent US8927536 (2015) BindingDB Entry DOI: 10.7270/Q2Q23XZP
					More data for this Ligand-Target Pair