BDBM142002 US8927536, 32

SMILES: Cn1cc(cn1)-c1ccc(cc1)C1(CC1)c1nnc2CC(C)(CO)SCCn12

InChI Key: InChIKey=PTXJDKXORGVEGX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM142002 (US8927536, 32) Show SMILES Cn1cc(cn1)-c1ccc(cc1)C1(CC1)c1nnc2CC(C)(CO)SCCn12 Show InChI InChI=1S/C21H25N5OS/c1-20(14-27)11-18-23-24-19(26(18)9-10-28-20)21(7-8-21)17-5-3-15(4-6-17)16-12-22-25(2)13-16/h3-6,12-13,27H,7-11,14H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	7.4	25
Daiichi Sankyo Company, Limited US Patent					Assay Description A reaction was performed on a 384-well plate (Greiner Bio One) using a reaction volume of 24 µL, and all the samples were diluted with an assay buffe...				US Patent US8927536 (2015) BindingDB Entry DOI: 10.7270/Q2Q23XZP
					More data for this Ligand-Target Pair