BDBM142048 US8927577, 29

SMILES: OC(=O)CCNC(=O)c1ccc(cc1)C(CC(F)(F)F)Nc1cnc2ccccc2c1

InChI Key: InChIKey=PFCUKTWRSRXTPS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142048   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Pro-glucagon (Homo sapiens (Human))	BDBM142048 (US8927577, 29) Show SMILES OC(=O)CCNC(=O)c1ccc(cc1)C(CC(F)(F)F)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C22H20F3N3O3/c23-22(24,25)12-19(28-17-11-16-3-1-2-4-18(16)27-13-17)14-5-7-15(8-6-14)21(31)26-10-9-20(29)30/h1-8,11,13,19,28H,9-10,12H2,(H,26,31)(H,29,30)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	930	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Pfizer Inc. US Patent					Assay Description The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptor. Test compoun...				US Patent US8927577 (2015) BindingDB Entry DOI: 10.7270/Q29S1PRV
					More data for this Ligand-Target Pair