BDBM142654 US8937068, 30

SMILES: Oc1ccc(cc1)-c1cnc2ccc(NC(=S)NCC=C)nc2n1

InChI Key: InChIKey=YKMUCILEPVJXKD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142654   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM142654 (US8937068, 30) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NC(=S)NCC=C)nc2n1 Show InChI InChI=1S/C17H15N5OS/c1-2-9-18-17(24)22-15-8-7-13-16(21-15)20-14(10-19-13)11-3-5-12(23)6-4-11/h2-8,10,23H,1,9H2,(H2,18,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Jnk1 & Jnk2 (Homo sapiens (Human))	BDBM142654 (US8937068, 30) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NC(=S)NCC=C)nc2n1 Show InChI InChI=1S/C17H15N5OS/c1-2-9-18-17(24)22-15-8-7-13-16(21-15)20-14(10-19-13)11-3-5-12(23)6-4-11/h2-8,10,23H,1,9H2,(H2,18,20,21,22,24)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM142654 (US8937068, 30) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NC(=S)NCC=C)nc2n1 Show InChI InChI=1S/C17H15N5OS/c1-2-9-18-17(24)22-15-8-7-13-16(21-15)20-14(10-19-13)11-3-5-12(23)6-4-11/h2-8,10,23H,1,9H2,(H2,18,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM142654 (US8937068, 30) Show SMILES Oc1ccc(cc1)-c1cnc2ccc(NC(=S)NCC=C)nc2n1 Show InChI InChI=1S/C17H15N5OS/c1-2-9-18-17(24)22-15-8-7-13-16(21-15)20-14(10-19-13)11-3-5-12(23)6-4-11/h2-8,10,23H,1,9H2,(H2,18,20,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8937068 (2015) BindingDB Entry DOI: 10.7270/Q2H993WP
					More data for this Ligand-Target Pair