BDBM144264 US8952008, 22
SMILES: CCS(=O)(=O)c1ccc(c(F)c1)-c1cc(ccc1F)-c1cnnc2n(cnc12)C1CC1
InChI Key: InChIKey=CHDRFSOETOBLIT-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GABA A receptor alpha-2/beta-2/gamma-2 (Homo sapiens (Human)) | BDBM144264 (US8952008, 22) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 67.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Limited US Patent | Assay Description The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per... | US Patent US8952008 (2015) BindingDB Entry DOI: 10.7270/Q2XD10DW | |||||||||||
More data for this Ligand-Target Pair |