null

SMILES: NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc([NH2+][O-])cc1

InChI Key: InChIKey=JHIDXHNBKLDKNG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 144585   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM144585 (US8969583, 1) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc([NH2+][O-])cc1 Show InChI InChI=1S/C18H24N6O4S/c19-16(25)14-15(12-2-4-13(22-27)5-3-12)23-29-17(14)21-18(26)20-6-1-7-24-8-10-28-11-9-24/h2-5H,1,6-11,22H2,(H2,19,25)(H2,20,21,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM144585 (US8969583, 1) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc([NH2+][O-])cc1 Show InChI InChI=1S/C18H24N6O4S/c19-16(25)14-15(12-2-4-13(22-27)5-3-12)23-29-17(14)21-18(26)20-6-1-7-24-8-10-28-11-9-24/h2-5H,1,6-11,22H2,(H2,19,25)(H2,20,21,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM144585 (US8969583, 1) Show SMILES NC(=O)c1c(NC(=O)NCCCN2CCOCC2)snc1-c1ccc([NH2+][O-])cc1 Show InChI InChI=1S/C18H24N6O4S/c19-16(25)14-15(12-2-4-13(22-27)5-3-12)23-29-17(14)21-18(26)20-6-1-7-24-8-10-28-11-9-24/h2-5H,1,6-11,22H2,(H2,19,25)(H2,20,21,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.4	30
Allergan, Inc. US Patent					Assay Description Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...				US Patent US8969583 (2015) BindingDB Entry DOI: 10.7270/Q2RN36JS
					More data for this Ligand-Target Pair