BDBM149332 US8962837, 19

SMILES: Cc1nnc(nc1C)N1CCC(CC1)Oc1cc(ccc1Cl)C(F)(F)F

InChI Key: InChIKey=PRDNSHYLILKQEH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stearoyl-CoA desaturase (Homo sapiens (Human))	BDBM149332 (US8962837, 19) Show SMILES Cc1nnc(nc1C)N1CCC(CC1)Oc1cc(ccc1Cl)C(F)(F)F Show InChI InChI=1S/C17H18ClF3N4O/c1-10-11(2)23-24-16(22-10)25-7-5-13(6-8-25)26-15-9-12(17(19,20)21)3-4-14(15)18/h3-4,9,13H,5-8H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	7.4	4
Pierre Fabre Medicament US Patent					Assay Description Human SCD-1 enzyme activity using HepG2 cell microsomes after treating with inhibitory compounds (% inhibition):Human hepatocarcinoma HepG2 cells (AT...				US Patent US8962837 (2015) BindingDB Entry DOI: 10.7270/Q2KS6Q8C
					More data for this Ligand-Target Pair