BDBM149450 US8975250, 32

SMILES: CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc(cc3OC)N3CCC(CC3)N3CCOCC3)nc12

InChI Key: InChIKey=OWSAIKUVTIRHEY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149450   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM149450 (US8975250, 32) Show SMILES CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc(cc3OC)N3CCC(CC3)N3CCOCC3)nc12 Show InChI InChI=1S/C26H34N8O4/c1-3-34-23(27)21(24(28)36)22(35)18-15-29-26(31-25(18)34)30-19-5-4-17(14-20(19)37-2)32-8-6-16(7-9-32)33-10-12-38-13-11-33/h4-5,14-16H,3,6-13,27H2,1-2H3,(H2,28,36)(H,29,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description The kinase activity of CaMKII beta is evaluated by means of a radioactive test on the recombinant CaMKII beta enzyme. The amount of ATP-gamma 33P in...				US Patent US8975250 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XD8
					More data for this Ligand-Target Pair