BDBM149455 US8975250, 75

SMILES: CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc4CNCCc4c3)nc12

InChI Key: InChIKey=ZQUKGJSMCUOBNN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 149455   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM149455 (US8975250, 75) Show SMILES CCn1c(N)c(C(N)=O)c(=O)c2cnc(Nc3ccc4CNCCc4c3)nc12 Show InChI InChI=1S/C19H21N7O2/c1-2-26-16(20)14(17(21)28)15(27)13-9-23-19(25-18(13)26)24-12-4-3-11-8-22-6-5-10(11)7-12/h3-4,7,9,22H,2,5-6,8,20H2,1H3,(H2,21,28)(H,23,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
SANOFI US Patent					Assay Description The kinase activity of CaMKII beta is evaluated by means of a radioactive test on the recombinant CaMKII beta enzyme. The amount of ATP-gamma 33P in...				US Patent US8975250 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XD8
					More data for this Ligand-Target Pair