BDBM150741 5-chloro-2-[(3-fluorophenyl)carbamoyl]phenyl diethyl phosphate (21)
SMILES: CCOP(=O)(OCC)Oc1cc(Cl)ccc1C(=O)Nc1cccc(F)c1
InChI Key: InChIKey=ANPIJEKAJCRTKL-UHFFFAOYSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Butyrylcholinesterase (BChE) (Equus caballus (Horse)) | BDBM150741 (5-chloro-2-[(3-fluorophenyl)carbamoyl]phenyl dieth...) | PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.15E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Charles University in Prague | Assay Description The reaction mixture containing phosphate buffer, AChE or BChE and chosen compounds was prepared and intensively stirred. In given times (5, 10, 15, ... | Bioorg Chem 58: 48-52 (2015) Article DOI: 10.1016/j.bioorg.2014.11.005 BindingDB Entry DOI: 10.7270/Q26D5RQ1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acetylcholinesterase (Electrophorus electricus (Electric eel)) | BDBM150741 (5-chloro-2-[(3-fluorophenyl)carbamoyl]phenyl dieth...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Charles University in Prague | Assay Description The reaction mixture containing phosphate buffer, AChE or BChE and chosen compounds was prepared and intensively stirred. In given times (5, 10, 15, ... | Bioorg Chem 58: 48-52 (2015) Article DOI: 10.1016/j.bioorg.2014.11.005 BindingDB Entry DOI: 10.7270/Q26D5RQ1 | |||||||||||
More data for this Ligand-Target Pair |