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SMILES: Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na]

InChI Key: InChIKey=YIUHPQDQDWZJIV-UHFFFAOYSA-M

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151630   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM151630
PNG
(US8987445, 10)
Show SMILES Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na]
Show InChI InChI=1S/C28H23F3N2O5S.Na/c1-17-23-4-2-3-5-24(23)25(19-8-9-19)32-26(17)33(16-18-6-12-21(13-7-18)38-28(29,30)31)39(36,37)22-14-10-20(11-15-22)27(34)35;/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35);/q;+1/p-1
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Similars
US Patent
n/an/a 1.90n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...

US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair