BDBM151644 US8987445, 35

SMILES: FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2Cl)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])cc1

InChI Key: InChIKey=PWOBWLLNWWITHV-UHFFFAOYSA-M

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151644   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151644 (US8987445, 35) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2Cl)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])cc1 Show InChI InChI=1S/C24H16ClF3N2O5S.Na/c25-21-20-4-2-1-3-17(20)13-29-22(21)30(14-15-5-9-18(10-6-15)35-24(26,27)28)36(33,34)19-11-7-16(8-12-19)23(31)32;/h1-13H,14H2,(H,31,32);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair