BDBM151702 US8987445, 137

SMILES: Cc1cccc2cnc(N(Cc3ccc(OC(F)(F)F)cc3)S(=O)(=O)c3ccc(cc3)C(O)=O)c(C)c12

InChI Key: InChIKey=ZDDHKJMZDYPJET-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151702   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM151702 (US8987445, 137) Show SMILES Cc1cccc2cnc(N(Cc3ccc(OC(F)(F)F)cc3)S(=O)(=O)c3ccc(cc3)C(O)=O)c(C)c12 Show InChI InChI=1S/C26H21F3N2O5S/c1-16-4-3-5-20-14-30-24(17(2)23(16)20)31(15-18-6-10-21(11-7-18)36-26(27,28)29)37(34,35)22-12-8-19(9-13-22)25(32)33/h3-14H,15H2,1-2H3,(H,32,33)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair