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SMILES: Cc1c(ncc2ccccc12)N(Cc1cc2CCCc2c(F)c1)S(=O)(=O)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=JIDVNEPLKJVKQM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151739   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM151739
PNG
(US8987445, 175)
Show SMILES Cc1c(ncc2ccccc12)N(Cc1cc2CCCc2c(F)c1)S(=O)(=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C27H23FN2O4S/c1-17-23-7-3-2-5-21(23)15-29-26(17)30(16-18-13-20-6-4-8-24(20)25(28)14-18)35(33,34)22-11-9-19(10-12-22)27(31)32/h2-3,5,7,9-15H,4,6,8,16H2,1H3,(H,31,32)
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PC sid
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Similars
US Patent
n/an/a 4.40n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...

US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair