BDBM151746 US8987445, 182
SMILES: Cc1cc2ccccc2nc1N(Cc1ccc(cc1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O
InChI Key: InChIKey=LZUAGULEUUAFOE-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human)) | BDBM151746![]() (US8987445, 182) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | 37 |
Mitsubishi Tanabe Pharma Corporation US Patent | Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy... | US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5 | |||||||||||
More data for this Ligand-Target Pair |