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SMILES: OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1cc2c(F)cc(F)cc2s1)c1ncc2ccccc2c1C1CC1

InChI Key: InChIKey=NNGBVZQEXQLSPG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 151748   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily M member 8


(Homo sapiens (Human))		BDBM151748
PNG
(US8987445, 184)
Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1cc2c(F)cc(F)cc2s1)c1ncc2ccccc2c1C1CC1
Show InChI InChI=1S/C28H20F2N2O4S2/c29-19-11-24(30)23-13-20(37-25(23)12-19)15-32(38(35,36)21-9-7-17(8-10-21)28(33)34)27-26(16-5-6-16)22-4-2-1-3-18(22)14-31-27/h1-4,7-14,16H,5-6,15H2,(H,33,34)
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Similars
US Patent
n/an/a 1.10n/an/an/an/an/a37



Mitsubishi Tanabe Pharma Corporation

US Patent


Assay Description
The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...

US Patent US8987445 (2015)


BindingDB Entry DOI: 10.7270/Q2BZ64R5
More data for this
Ligand-Target Pair