BDBM151750 BDBM151751::US8987445, 186

SMILES: OC(=O)c1ccc(cc1)S(=O)(=O)N(C1CCc2cc(OC(F)(F)F)ccc12)c1ncc2ccccc2c1C1CC1

InChI Key: InChIKey=RLONLJJPXIVWOF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 151750   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM151750 (BDBM151751 | US8987445, 186) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(C1CCc2cc(OC(F)(F)F)ccc12)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H23F3N2O5S/c30-29(31,32)39-21-10-13-23-19(15-21)9-14-25(23)34(40(37,38)22-11-7-18(8-12-22)28(35)36)27-26(17-5-6-17)24-4-2-1-3-20(24)16-33-27/h1-4,7-8,10-13,15-17,25H,5-6,9,14H2,(H,35,36)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (TRPM8) (Homo sapiens (Human))	BDBM151750 (BDBM151751 | US8987445, 186) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(C1CCc2cc(OC(F)(F)F)ccc12)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H23F3N2O5S/c30-29(31,32)39-21-10-13-23-19(15-21)9-14-25(23)34(40(37,38)22-11-7-18(8-12-22)28(35)36)27-26(17-5-6-17)24-4-2-1-3-20(24)16-33-27/h1-4,7-8,10-13,15-17,25H,5-6,9,14H2,(H,35,36)	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair